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Lose weight somavert. This was an important milestone because at that time it was not conceivable to modify an enzyme so extensively still maintain its activity. PEGylation was first described in the 1970s by Davies reported in two key papers on albumin , catalase modification [ 6, Abuchowsky 7].

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PEGylation was first described in the 1970s by Davies and Abuchowsky and reported in two key papers on albumin and catalase modification [ 6, 7]. This was an important milestone, because at that time it was not conceivable to modify an enzyme so extensively and still maintain its activity.

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